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A simple procedure for obtaining fetal chromosome preparations from bloodstained amniotic fluid
Author(s) -
Watt Jessie L.,
Laing Elizabeth J.
Publication year - 1982
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970020211
Subject(s) - amniocentesis , amniotic fluid , phytohaemagglutinin , prenatal diagnosis , fetus , medicine , andrology , amniotic sac , obstetrics , pregnancy , biology , immunology , lymphocyte , genetics
Two patients undergoing amniocentesis are described in which the resulting amniotic fluid was unavoidably bloodstained. The results suggest that it may be beneficial in such cases to reserve a small volume of bloodstained liquor for culture with phytohaemagglutinin since the presence of a few fetal lymphocytes can lead to a prenatal diagnosis within 72 h.