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Amniotic fluid pregnancy‐specific β 1 ‐glycoprotein (SP 1 ) in Meckel's syndrome: A new test for prenatal diagnosis?
Author(s) -
Heikinheimo Markku,
Aula Pertti,
Rapola Juhani,
Wahlström Torsten,
Jalanko Hannu,
Seppälä Markku
Publication year - 1982
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970020205
Subject(s) - amniotic fluid , pregnancy , medicine , prenatal diagnosis , glycoprotein , obstetrics , andrology , fetus , gynecology , biology , genetics
Abstract Amniotic fluid levels of pregnancy‐specific β 1 ‐glycoprotein (SP 1 ) were elevated in four pregnancies with Meckel's syndrome at 16 and 26 weeks, and the levels of hCG were also elevated in three out of four cases. These findings suggest a potential new application of SP 1 measurement for prenatal diagnosis.