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Fetal sexing in possible carriers for duchenne muscular dystrophy
Author(s) -
Bundey Sarah,
Ebdy Jacqueline
Publication year - 1982
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970020102
Subject(s) - sexing , duchenne muscular dystrophy , fetus , amniocentesis , miscarriage , obstetrics , medicine , aborted fetus , prenatal diagnosis , muscular dystrophy , pregnancy , gynecology , biology , genetics
Abstract Over a five‐year period in the West Midlands there were 34 pregnancies to women who were possible carriers for Duchenne muscular dystrophy and who were known to the Department of Clinical Genetics. Fetal sexing was performed in only ten of 26 pregnancies to women of high or moderate risk, and of the five male fetuses discovered, only two were aborted. Overall, the 34 pregnancies resulted in one miscarriage, 14 males (of whom two were aborted and two were affected) and 19 females. Information was also obtained on five further possible carriers who were ascertained solely because they had an amniocentesis. These five pregnancies led to the birth of one affected male and to the termination of one male fetus.