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A case of a paracentric inversion inv(7)(q11q22). Prenatal detection and counselling
Author(s) -
Ridler Michael A. C.,
Sutton Simon D.
Publication year - 1981
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1970010113
Subject(s) - chromosomal inversion , prenatal diagnosis , medicine , obstetrics , genetics , gynecology , biology , pregnancy , fetus , karyotype , gene , chromosome
Abstract A paracentric inversion in the long arm of a number 7 chromosome was detected in an amniotic cell culture from a 41 year old woman, screened because of maternal age. The karyotype was 46, XX, inv(7) (q11q22). Her husband carried an identical inversion. The parents were advised that the pregnancy should continue and a healthy infant was born at term. Prenatal diagnosis and counselling for paracentric inversion heterozygotes are discussed in the light of published and unpublished cases.