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Prenatal magnetic resonance imaging of optic nerve head coloboma
Author(s) -
Righini Andrea,
Avagliano Laura,
Doneda Chiara,
Pinelli Lorenzo,
Parazzini Cecilia,
Rustico Mariangela,
Triulzi Fabio,
Bulfamante Gaetano
Publication year - 2008
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1955
Subject(s) - coloboma , optic nerve , medicine , microphthalmos , magnetic resonance imaging , microphthalmia , optic nerve hypoplasia , ophthalmology , anatomy , radiology , biology , biochemistry , gene
Objective Congenital optic nerve head coloboma represents an important cause of childhood visual impairment and blindness; it can be isolated or, more often, it can be associated with several syndromes. Ultrasound has limitations in depicting the posterior aspect of the fetal eye globe, so prenatal information about ocular coloboma are very scarce. The purpose of this paper was to report prenatal magnetic resonance (MR) imaging features of optic nerve head coloboma. Methods MR imaging at 1.5 Tesla was based on multiplanar single‐shot fast spin‐echo T2‐weighted 3–4 mm thick contiguous sections. Results Three fetal cases with optic nerve head coloboma and one with microphthalmos and colobomatous cyst are reported. Coloboma appeared as a focal bulging of ocular globe profile at the insertion of optic nerve. Conclusion Prenatal MR imaging allowed an accurate diagnosis to be obtained. Copyright © 2008 John Wiley & Sons, Ltd.