Color Doppler ultrasound of spiral artery blood flow for prediction of hypertensive disorders and intra uterine growth restriction: a longitudinal study | Zendy

Deurloo K. L. | Zendy; Spreeuwenberg M. D. | Zendy; Bolte A. C. | Zendy; Van Vugt J. M. G. | Zendy

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Color Doppler ultrasound of spiral artery blood flow for prediction of hypertensive disorders and intra uterine growth restriction: a longitudinal study

Author(s) -

Deurloo K. L.,

Spreeuwenberg M. D.,

Bolte A. C.,

Van Vugt J. M. G.

Publication year - 2007

Publication title -

prenatal diagnosis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.956

H-Index - 97

eISSN - 1097-0223

pISSN - 0197-3851

DOI - 10.1002/pd.1822

Subject(s) - gestation , medicine , preeclampsia , uterine artery , intrauterine growth restriction , gestational age , blood flow , fetus , pregnancy , obstetrics , cardiology , biology , genetics

Objective To construct reference ranges for spiral artery (SA) flow velocities and examine the possibility to predict intra uterine growth restricted (IUGR) fetuses, pregnancy‐induced hypertension (PIH) and/or preeclampsia. Methods Spiral artery flow velocity measurements were performed using Color Doppler between 11 to 13 + 6, between 14 to 17 + 6 and between 18 to 24 weeks of gestation, each measurement was performed twice. Spiral artery flow velocities were analyzed with multilevel modeling: individual regression curves were estimated and combined to obtain the reference intervals for SA flow velocities in normal pregnancies. Mann–Whitney U tests was used to compare the deviation from expected flow velocity between normal and complicated pregnancies. Results One hundred and eight pregnancies were included; 4 pregnancies were complicated with preeclampsia, 10 pregnancies with IUGR fetuses (

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