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Prenatal diagnosis of tracheo‐oesophageal fistula and oesophageal atresia
Author(s) -
Choudhry M.,
Boyd P. A.,
Chamberlain P. F.,
Lakhoo K
Publication year - 2007
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1745
Subject(s) - medicine , prenatal diagnosis , ultrasound , atresia , fistula , stomach , tracheoesophageal fistula , radiology , fetus , gastroenterology , surgery , pregnancy , biology , genetics
Objectives To assess the accuracy of the prenatal ultrasound finding of subjectively small/absent stomach bubble in the prenatal diagnosis of tracheo‐oesophageal fistula and oesophageal atresia (TOF/OA). Methods A retrospective study of prenatal ultrasound scans showing small/absent stomach bubble was carried out between 1st January 1994 and 31st December 2003. Results There were 62 cases with prenatally suspected ( n = 40) and/or post‐natally diagnosed ( n = 22) TOF/OA. Among the 40 cases of prenatally suspected TOF/OA 15 were thought to be isolated and 25 non‐isolated. Of the 15 suspected isolated cases, 7 were normal and 8 had TOF/OA (5 isolated + 3 TOF/OA with another anomaly) at delivery. Among the 25 cases of prenatally suspected non‐isolated TOF/OA, there was confirmation in only two cases, in the remaining 23 cases other anomalies were confirmed but TOF/OA was not present. Twenty‐two babies with TOF/OA were identified in whom there had been no prenatal ultrasound suspicion on ultrasound scanning. Six had isolated TOF/OA and 16 had non‐isolated TOF/OA. Conclusion Of the 32 cases of confirmed TOF/OA,10 (31%) were suspected prenatally. If the TOF/OA was an isolated anomaly (11 cases), the prenatal detection rate was 45%. Interpretation of ultrasound findings suspicious of TOF/OA requires caution, particularly, when there are associated multiple anomalies on scan. Copyright © 2007 John Wiley & Sons, Ltd.