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Prenatal thrombosis of the inferior vena cava and the renal veins
Author(s) -
Smorgick Noam,
Herman Arie,
Wiener Yifat,
Halperin Reuvit,
Sherman Dan
Publication year - 2007
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1739
Subject(s) - medicine , inferior vena cava , thrombosis , prenatal diagnosis , fetus , pregnancy , vena cava , cardiology , radiology , biology , genetics
Objective This manuscript discusses the clinical presentation, diagnosis, pathophysiology and possible etiologies of prenatal thrombosis of the inferior vena cava and renal veins. Methods Eleven cases were identified through a Medline search of the English literature. These cases were reviewed, together with a recent case that was treated in our medical center. Results Fetal thrombosis in the aforementioned vessels, presented as hydrops fetalis (33%), acute fetal distress (42%), or as an incidental prenatal ultrasound finding (25%). Underlying maternal conditions were present in 58%, and included chronic conditions (hypertension and diabetes mellitus), acute conditions (pyelonephritis and preeclampsia) and thrombophilia. In 42% cases, the prenatal ultrasound scan revealed an enlarged and hyper‐echogenic affected kidney. Conclusion Intrauterine fetal venous thrombosis is a rare phenomenon, probably attributed to a multifactorial process. These factors may include inherited thrombophilia as well as prothrombotic clinical conditions. Copyright © 2007 John Wiley & Sons, Ltd.