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Abnormal abdominal situs: what and how should we look for?
Author(s) -
Salomon Laurent J.,
Baumann Clarisse,
Delezoide AnneLise,
Oury JeanFrançois,
Pariente Danièle,
Sebag Guy,
Garel Catherine
Publication year - 2006
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1401
Subject(s) - medicine , amniocentesis , fetus , abdominal ultrasound , situs inversus , prenatal diagnosis , polysplenia , radiology , anatomy , pregnancy , genetics , biology
Background Prenatal management of abnormal abdominal situs is challenging since prognosis is highly variable depending on the associated malformations. Methods The authors report on two cases of ambiguous abdominal situs. Prenatal management included specialized ultrasound examination of fetal anatomy and heart, amniocentesis for determination of the fetal karyotype and fetal abdominal MR. Results In both cases, abnormal situs was associated with other abdominal anomalies such as azygous continuation, biliary atresia, bowel obstruction and polysplenia. Fetal MR was a useful additional tool in the assessment of fetal abdominal anatomy in both cases. Conclusions On the basis of these reports, the literature is reviewed and a prenatal management scheme is proposed. Copyright © 2006 John Wiley & Sons, Ltd.