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Prenatal screening for Down syndrome and neural tube defects in twin pregnancies
Author(s) -
Wald Nicholas J.,
Rish Simon
Publication year - 2005
Publication title -
prenatal diagnosis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.956
H-Index - 97
eISSN - 1097-0223
pISSN - 0197-3851
DOI - 10.1002/pd.1258
Subject(s) - neural tube , prenatal diagnosis , down syndrome , obstetrics , medicine , neural tube defect , pregnancy , prenatal screening , congenital disease , pediatrics , fetus , genetics , biology , psychiatry , embryo
Prenatal screening and diagnosis in a twin pregnancy is not straightforward. Once a twin pregnancy has been identified, women and their partners need time to consider the implications and decide whether they wish the pregnancy to be screened for Down syndrome or neural tube defects. We discuss here how multiple marker screening for Down syndrome and alpha‐fetoprotein screening for neural tube defects can be carried out, given that this is the parents' chosen option and that the health professionals involved are capable of performing a diagnosis and selective feticide, should this arise. Copyright © 2005 John Wiley & Sons, Ltd.