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Quantitative analysis of flavonol glycosides in Ginkgo biloba : a comparison of two analytical methods
Author(s) -
Gray D. E.,
Upton R.,
Chandra A.,
Porter A.,
Harris R. K.
Publication year - 2005
Publication title -
phytochemical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 72
eISSN - 1099-1565
pISSN - 0958-0344
DOI - 10.1002/pca.886
Subject(s) - chemistry , ginkgo biloba , pharmacopoeia , chromatography , glycoside , nutraceutical , organic chemistry , pharmacology , food science , medicine , alternative medicine , pathology
A comparison of testing methods for constituents of Ginkgo biloba was performed as part of the process for determining which of the many available analytical methods was most appropriate for inclusion in the American Herbal Pharmacopoeia (AHP). Three primary methods were reviewed: those adopted by the European Pharmacopoeia, the National Science Foundation–Institute for Nutraceutical Advancement (NSF‐INA) and the United States Pharmacopeia . Methods were compared by evaluating sample preparation and hydrolysis, precision and methods of total flavonol glycoside calculation by two independent laboratories. The AHP adopted the method of NSF‐INA for inclusion in the AHP monograph owing to observed superiority of this method in terms of precision, glycoside calculation, ease of sample preparation and chromatographic parameters. Copyright © 2005 John Wiley & Sons, Ltd.