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Phytochemical profiling of new and old world Hypericum (St. John's Wort) species
Author(s) -
Crockett Sara L.,
Schaneberg Brian,
Khan Ikhlas A.
Publication year - 2005
Publication title -
phytochemical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 72
eISSN - 1099-1565
pISSN - 0958-0344
DOI - 10.1002/pca.875
Subject(s) - hypericum perforatum , phytochemical , chemistry , hypericum , traditional medicine , hypericin , botany , pharmacology , biology , biochemistry , medicine
Botanical extracts of Hypericum perforatum L. (common St. John's Wort) are used in the USA and in Europe as a treatment for mild to moderate depression, although controversy surrounds the identity of the active constituent(s). RP‐HPLC with photodiode array detection was used to separate and quantify nine compounds of pharmacological interest in extracts from 74 taxa of Hypericum native to the Old and New World. Chemical profiles of these constituents may be used to distinguish extracts of H. perforatum from those of other species of Hypericum , and to indicate species that may be of interest for further phytochemical investigation. Copyright © 2005 John Wiley & Sons, Ltd.