Premium
The enhanced role of a lanthanide shift reagent in the structure elucidation and 1 H NMR and 13 C NMR characterization of some marine natural products
Author(s) -
Wright Anthony D.,
König Gabriele M.,
Sticher Otto
Publication year - 1992
Publication title -
phytochemical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 72
eISSN - 1099-1565
pISSN - 0958-0344
DOI - 10.1002/pca.2800030207
Subject(s) - chemistry , lanthanide , reagent , europium , carbon 13 nmr , proton nmr , proton , tris , stereochemistry , crystallography , organic chemistry , ion , biochemistry , physics , quantum mechanics
Three marine‐derived natural products, 1, 2 and 3, were used to demonstrate the enhanced role of a lanthanide shift reagent [Europium(III)‐tris(1,1,1,2,2,3,3)‐heptafluoro‐7,7‐dimethyl‐ d 6 ‐octa‐4,6‐dion‐ d 3 , C 30 H 3 D 27 EuF 21 O 6 , (Eu(fod) 3 )] in the structure elucidation of compounds containing a single hydroxyl function. The value of reagents of this type, both as an aid to structure solution as well as in the complete assignment of 1 H NMR and 13 C NMR resonances, is clearly demonstrated as a consequence of the development of proton‐detected proton‐carbon correlated 2D‐NMR methodologies.