Premium
The enhanced role of a lanthanide shift reagent in the structure elucidation and 1 H NMR and 13 C NMR characterization of some marine natural products
Author(s) -
Wright Anthony D.,
König Gabriele M.,
Sticher Otto
Publication year - 1992
Publication title -
phytochemical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 72
eISSN - 1099-1565
pISSN - 0958-0344
DOI - 10.1002/pca.2800030207
Subject(s) - chemistry , lanthanide , reagent , europium , carbon 13 nmr , proton nmr , proton , tris , stereochemistry , crystallography , organic chemistry , ion , biochemistry , physics , quantum mechanics
Three marine‐derived natural products, 1, 2 and 3, were used to demonstrate the enhanced role of a lanthanide shift reagent [Europium(III)‐tris(1,1,1,2,2,3,3)‐heptafluoro‐7,7‐dimethyl‐ d 6 ‐octa‐4,6‐dion‐ d 3 , C 30 H 3 D 27 EuF 21 O 6 , (Eu(fod) 3 )] in the structure elucidation of compounds containing a single hydroxyl function. The value of reagents of this type, both as an aid to structure solution as well as in the complete assignment of 1 H NMR and 13 C NMR resonances, is clearly demonstrated as a consequence of the development of proton‐detected proton‐carbon correlated 2D‐NMR methodologies.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom