Premium
The application of high‐speed countercurrent chromatography to the semipreparative separation of vincamine and vincine
Author(s) -
Zhou JinYun,
Fang QiCheng,
Lee YuWei
Publication year - 1990
Publication title -
phytochemical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 72
eISSN - 1099-1565
pISSN - 0958-0344
DOI - 10.1002/pca.2800010205
Subject(s) - chemistry , countercurrent chromatography , chromatography , high performance liquid chromatography , resolution (logic) , high resolution , chromatographic separation , artificial intelligence , remote sensing , computer science , geology
Abstract High‐speed countercurrent chromatography (HSCCC) has gained increasing popularity in the isolation of bioactive natural products. This paper reports its application to the separation of the alkaloids vincamine and vincine which differ only by a methoxy group. It is demonstrated in this study that the resolution and speed of HSCCC is comparable to high‐performance liquid chromatography (HPLC) and its capability in semi‐preparative purification via continuous sample injections can be a very useful application in phytochemical research·alkaloids; vincamine; vincine; high‐speed countercurrent chromatography