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Centrifugal partition chromatography in the separation of natural products
Author(s) -
Marston A.,
Slacanin I.,
Hostettmann K.
Publication year - 1990
Publication title -
phytochemical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 72
eISSN - 1099-1565
pISSN - 0958-0344
DOI - 10.1002/pca.2800010102
Subject(s) - chemistry , chromatography , aqueous solution , polar , cartridge , separation method , countercurrent chromatography , solvent , partition (number theory) , high performance liquid chromatography , organic chemistry , mechanical engineering , physics , mathematics , combinatorics , astronomy , engineering
Abstract Recent innovations in liquid/liquid chromatographic techniques have led to a resurgence of interest in their use for the separation of natural products. Commercially available instruments which rely on centrifugal acceleration to speed up separation times are based either on a battery of cartridges or on a rotating multilayer coil and can be employed either as analytical tools or for preparative purposes. While solvent consumption is low, milligram to gram quantities are capable of being separated. Aqueous and non‐aqueous two‐phase solvent systems are compatible with these techniques and numerous applications involving simple and complex mixtures of natural products, both polar and non‐polar, have been demonstrated.