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Discrimination of Cynanchum wilfordii and Cynanchum auriculatum by terahertz spectroscopic analysis
Author(s) -
Ham Woo Sik,
Kim Jinju,
Park Dae Joon,
Ryu HanCheol,
Jang Young Pyo
Publication year - 2018
Publication title -
phytochemical analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.574
H-Index - 72
eISSN - 1099-1565
pISSN - 0958-0344
DOI - 10.1002/pca.2751
Subject(s) - terahertz radiation , chemistry , traditional medicine , spectroscopy , chromatography , analytical chemistry (journal) , terahertz spectroscopy and technology , materials science , physics , optoelectronics , medicine , quantum mechanics
Abstract Introduction Precise identification of botanical origin of plant species is crucial for the quality control of herbal medicine. In Korea, the root part of Cynanchum auriculatum has been misused for C. wilfordii in the herbal drug market due to their morphological similarities. Currently, DNA analysis using the polymerase chain reaction (PCR) method is employed to discriminate between these species. Objective In order to develop a new analytical tool for the rapid discrimination of C. wilfordii and C. auriculatum , terahertz (THz) spectroscopy was employed. Methodology Authentic samples of C. wilfordii and C. auriculatum were provided from the National Institute and standardized pellets for each species were prepared to get optimum results with terahertz time‐domain spectroscopy (THz‐TDS) in frequency range 0.2–1.20 THz. Results The C. wilfordii pellet showed longer time delay compare to the sample of C. auriculatum and this was due to the difference in permittivity. The pellet samples of C. wilfordii and C. auriculatum showed a permittivity difference of about 0.08 at 0.2–1.20 THz. Conclusion The experimental results indicated that THz‐TDS analysis can be an effective and rapid method for the discrimination of C. wilfordii and C. auriculatum , and this application can be expanded for the discrimination of other similar herbal medicines.