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Preparation and in vitro, bulk, and surface investigation of chitosan/graphene oxide composite films
Author(s) -
Pandele Andreea Madalina,
Dinescu Sorina,
Costache Marieta,
Vasile Eugenia,
Obreja Cosmin,
Iovu Horia,
Ionita Mariana
Publication year - 2013
Publication title -
polymer composites
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.577
H-Index - 82
eISSN - 1548-0569
pISSN - 0272-8397
DOI - 10.1002/pc.22620
Subject(s) - materials science , biocompatibility , chitosan , graphene , composite material , composite number , oxide , fourier transform infrared spectroscopy , thermogravimetric analysis , scanning electron microscope , ultimate tensile strength , transmission electron microscopy , chemical engineering , nanotechnology , engineering , metallurgy
Chitosan/graphene oxide (GO) composite films were prepared by solution blending method. Intensive characterization of films, surface, and bulk, was performed by Fourier transmission infrared spectrometry, X‐ray diffraction, scanning and transmission electron microscopy, thermal gravimetric analysis, and mechanical test. The biocompatibility of chitosan/GO films was tested in vitro on the murine osteoblastic cell line MC3T3‐E1. By incorporating 6 wt% GO into chitosan, Young's modulus and tensile strength values exceed those of nacre by about 60 and 20%, respectively. Biocompatibility assays indicated a high cell proliferation rate for the composite films with high GO content. POLYM. COMPOS., 34:2116–2124, 2013. © 2013 Society of Plastics Engineers