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Development and characterization of size controlled polymeric microcapsules loaded with superparamagnetic nanoparticles
Author(s) -
Zhang Xiangyu,
Xue Li,
Wang Jun,
Li Zhanshuang,
Liu Qi,
Zhang Milin,
Jing Xiaoyan,
Liu Lianhe
Publication year - 2013
Publication title -
polymer composites
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.577
H-Index - 82
eISSN - 1548-0569
pISSN - 0272-8397
DOI - 10.1002/pc.22429
Subject(s) - materials science , superparamagnetism , crystallinity , scanning electron microscope , nanoparticle , particle size , coprecipitation , fourier transform infrared spectroscopy , chemical engineering , polymer , composite number , particle size distribution , composite material , analytical chemistry (journal) , nanotechnology , magnetization , organic chemistry , chemistry , physics , quantum mechanics , magnetic field , engineering
Biocompatible polymeric microcapsules encapsulated Fe 3 O 4 nanoparticles were fabricated by double emulsion solvent evaporation method. Magnetic nanoparticles were synthesized by coprecipitation of iron oxide. scanning electron microscopy, transmission electron microscope, fourier transform infrared spectroscopy, X‐ray diffraction spectroscopy, and vibrating sample magnetometer were used to determine the morphology, structure, crystallinity, and saturation magnetization of the microcapsules, respectively. The results indicate that the composite microcapsules have nitrogen gas in the core, Fe 3 O 4 in the internal cavity with mean diameter of 3.6 μm. Thus, the alcohol as additive was applied to control the average size and size distribution of the microcapsules. Laser particle analyzer measurements indicate that the average size and size distribution decrease with the increasing of alcohol concentration, additionally the size and size distribution increase at higher alcohol concentration. Moreover, the prepared magnetic microcapsules with the coating of polymer have superparamagnetic behavior. Furthermore, the size controlled polymeric composite microcapsules have potential to act as ultrasound contrast agents and magnetic triggered drug delivery system. POLYM. COMPOS., 2013. © 2013 Society of Plastics Engineers