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Adrenocortical tumours in children and adolescents: The EXPeRT/PARTNER diagnostic and therapeutic recommendations
Author(s) -
Virgone Calogero,
Roganovic Jelena,
Vorwerk Peter,
Redlich Antje,
Schneider Dominik T.,
Janic Dragana,
Bien Ewa,
LópezAlmaraz Ricardo,
Godzinski Jan,
Osterlundh Gustaf,
StachowiczStencel Teresa,
Brugières Laurence,
Brecht Ines B.,
ThomasTeinturier Cécile,
Fresneau Brice,
Surun Aurore,
Ferrari Andrea,
Bisogno Gianni,
Orbach Daniel
Publication year - 2021
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.29025
Subject(s) - medicine , pediatrics , adrenocortical carcinoma , intensive care medicine , pathology
Abstract Adrenocortical tumours (ACTs) are rare during childhood. A complete surgical resection provides the best chance of cure, but the role and efficacy of the adjuvant therapy are still controversial. Various histologic criteria of malignancy for ACTs adopted in children do not facilitate comparative studies and are not completely shared. Therefore, a sharp demarcation between benign and malignant lesions has not been recognised, making it difficult to identify who potentially needs perioperative therapy. This manuscript presents the internationally harmonised recommendations for the diagnosis and treatment of ACTs in children and adolescents, established by the European Cooperative Study Group for Paediatric Rare Tumours (EXPeRT) group within the EU‐funded project PARTNER (Paediatric Rare Tumours Network ‐ European Registry).