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Metastatic neuroblastoma masquerading as infantile hemangioma in a 4‐month‐old child
Author(s) -
Karkoska Kristine,
Ricci Kiersten,
VandenHeuvel Katherine,
Trout Andrew T.,
Smith Ethan A.,
Kotagal Meera,
Weiss Brian
Publication year - 2021
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.28920
Subject(s) - medicine , hepatosplenomegaly , differential diagnosis , neuroblastoma , infantile hemangioma , pediatrics , hemangioma , radiology , pathology , disease , biology , genetics , cell culture
Abstract Introduction Diffuse liver lesions in an infant have a differential diagnosis including infantile hemangioma (IH), which is common in the first year of life, and neuroblastoma (NBL) which presents at a median age of 18 months. Results We describe the case of a 4‐month‐old girl with a known superficial/deep IH who presented with new axillary nodules and hepatosplenomegaly, initially suspected to reflect IH but later determined to be widely metastatic NBL. Conclusion Hepatic IH and metastatic NBL can present similarly. Clinicians must maintain a broad differential when evaluating new findings in a patient with previously diagnosed IH.