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Pediatric ovarian Sertoli‐Leydig cell tumors with heterologous rhabdomyosarcoma elements: Clinical case series and review of the literature
Author(s) -
Koo Jane,
Garrington Timothy P.,
Kerr Karol,
Treece Amy L.,
Cost Carrye R.
Publication year - 2020
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.28621
Subject(s) - heterologous , medicine , rhabdomyosarcoma , adjuvant , chemotherapy , germ cell tumors , pediatric oncology , oncology , pathology , sarcoma , cancer , biology , biochemistry , gene
Abstract Sertoli‐Leydig cell tumors (SLCTs) are rare ovarian neoplasms in pediatric patients. More exceedingly rare are SLCTs that also contain heterologous rhabdomyosarcoma (RMS) elements. For these patients, there is no standardized treatment. We report four cases of pediatric SLCT with heterologous RMS elements that were successfully treated with surgical resection and adjuvant chemotherapy. All four patients are alive and remain in remission.