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Successful use of transarterial radioembolization with yttrium‐90 (TARE‐Y90) in two children with hepatoblastoma
Author(s) -
Aguado Allison,
Dunn Stephen P.,
Averill Lauren W.,
Chikwava Kudakwashe R.,
Gresh Renee,
Rabinowitz Deborah,
Katzenstein Howard M.
Publication year - 2020
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.28421
Subject(s) - hepatoblastoma , medicine , chemotherapy , radiology , surgical resection , oncology
Primary malignant liver tumors are rare but all require surgical resection as part of therapy with curative intent. A minority of patients have resectable tumors at diagnosis. Chemotherapy has a therapeutic role in hepatoblastoma but only one‐third of patients have resectable disease at diagnosis. Two children with hepatoblastoma and suboptimal responses to initial chemotherapy received therapy with transarterial radioembolization utilizing yttrium‐90 (TARE‐Y90) and had significant response leading to resection and remission. The role of TARE‐Y90 needs to be studied further to define its use in primary pediatric liver neoplasms.