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Rare non‐Hodgkin lymphoma of childhood and adolescence: A consensus diagnostic and therapeutic approach to pediatric‐type follicular lymphoma, marginal zone lymphoma, and nonanaplastic peripheral T‐cell lymphoma
Author(s) -
Attarbaschi Andishe,
Abla Oussama,
Arias Padilla Laura,
Beishuizen Auke,
Burke G. A. Amos,
Brugières Laurence,
Bruneau Julie,
Burkhardt Birgit,
d'Amore Emanuele S. G.,
Klapper Wolfram,
Kontny Udo,
Pillon Marta,
Taj Mary,
Turner Suzanne D.,
Uyttebroeck Anne,
Woessmann Wilhelm,
Mellgren Karin
Publication year - 2020
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.28416
Subject(s) - medicine , lymphoma , anaplastic large cell lymphoma , follicular lymphoma , not otherwise specified , marginal zone , lymphoblastic lymphoma , large cell , marginal zone b cell lymphoma , pathology , oncology , b cell , t cell , immunology , cancer , adenocarcinoma , immune system , antibody
Pediatric‐type follicular (PTFL), marginal zone (MZL), and peripheral T‐cell lymphoma (PTCL) account each for <2% of childhood non‐Hodgkin lymphoma. We present clinical and histopathological features of PTFL, MZL, and few subtypes of PTCL and provide treatment recommendations. For localized PTFL and MZL, watchful waiting after complete resection is the therapy of choice. For PTCL, therapy is subtype‐dependent and ranges from a block‐like anaplastic large cell lymphoma (ALCL)‐derived and, alternatively, leukemia‐derived therapy in PTCL not otherwise specified and subcutaneous panniculitis‐like T‐cell lymphoma to a block‐like mature B‐NHL‐derived or, preferentially, ALCL‐derived treatment followed by hematopoietic stem cell transplantation in first remission in hepatosplenic and angioimmunoblastic T‐cell lymphoma.