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Wilms tumors and their precursors: Radiological diagnosis versus histology
Author(s) -
Dzhuma Kristina,
Ducou Le Pointe Hubert,
Coulomb Aurore,
Tabone MarieDominique,
Bergeron Christophe,
Audry Georges,
Irtan Sabine
Publication year - 2020
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.28414
Subject(s) - medicine , histology , radiological weapon , wilms' tumor , wilms tumour , radiology , kidney disease , pathology
The radiological distinction of Wilms tumor (WT) nodules from nephrogenic rests (NR) in patients with multifocal unilateral WT or bilateral disease is challenging. The study aims to compare the radiology assessment of kidney nodules with their final histology in 48 patients. The final histology of 118 nodules corresponded to the initial radiological diagnosis while 40 (25%) nodules were misdiagnosed, 20 being initially diagnosed WT on imaging were proved to be NR at histology. The size of nodules at diagnosis might help to distinguish WT from NR before surgery. Homogeneity did not seem to be a key feature.