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Catheter‐directed thrombolysis for submassive pulmonary embolism in children: A case series
Author(s) -
Belsky Jennifer,
Warren Patrick,
Stanek Joseph,
Kumar Riten
Publication year - 2020
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.28144
Subject(s) - medicine , pulmonary embolism , thrombolysis , radiological weapon , thrombus , incidence (geometry) , catheter , retrospective cohort study , radiology , pulmonary hypertension , myocardial infarction , physics , optics
Incidence of venous thromboembolism, including pulmonary embolism (PE), continues to rise in children. Optimum management of submassive PE is unclear. The principal objective of this retrospective study was to investigate the radiological and clinical outcomes in children with submassive PE treated with catheter‐directed thrombolysis (CDT). Five patients underwent six episodes of CDT. No patient developed major/clinically relevant non‐major bleeding. Most patients had complete radiological thrombus resolution and no patient had evidence of chronic thromboembolic pulmonary hypertension. There is an urgent need for larger prospective cohort studies/randomized controlled trials to investigate the role of CDT in pediatric PE.