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Bevacizumab in treating the cystic components of pediatric low‐grade gliomas: A report of four patients
Author(s) -
Levenbaum Erica,
Ellika Shehanaz,
Korones David N.
Publication year - 2019
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.27917
Subject(s) - bevacizumab , medicine , glioma , oncology , chemotherapy , cancer research
Low‐grade gliomas (LGG) are among the most common types of brain tumors in children and young adults. These tumors often consist of solid and cystic components. Bevacizumab is a documented treatment for progressive LGG, yet the impact of therapy on the cystic component of these tumors is unknown. We present four patients with prominently cystic LGG treated with bevacizumab at the time of progression. In each case, the cystic component responded to treatment. This is the first known study to investigate bevacizumab's impact on the cystic component of low‐grade gliomas.