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Validation of the school age self‐administered pediatric bleeding questionnaire (Self‐PBQ) in children aged 8–12 years
Author(s) -
Bui Jessica,
Martyres David,
James Paula D.,
Grabell Julie,
Wu John,
Steele MacGregor,
Silva Mariana,
Rand Margaret L.,
Blanchette Victor S.,
Barrowman Nick,
Klaassen Robert J.
Publication year - 2019
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.27709
Subject(s) - medicine , von willebrand disease , pediatrics , debriefing , intraclass correlation , clinical psychology , psychometrics , platelet , von willebrand factor , medical education
Background In the pediatric population, pathologic bleeding is often challenging to identify. The pediatric bleeding questionnaire (PBQ) was developed as a screening tool for von Willebrand disease (VWD) but was designed to be self‐completed by children above 12 years of age. The study objective was to determine whether a modified Self‐PBQ could be completed by 8‐ to 12‐year‐old children with adult assistance. Procedure The initial phase involved seven children who underwent cognitive debriefing to identify problems in the questionnaire, resulting in modifications to wording and response options. In phase 2, children completed the modified Self‐PBQ independently or with assistance from their parent at five Canadian treatment centers. Parents filled out the Self‐PBQ separately to serve as a comparison. Bleeding scores derived from the child self‐report were compared to those of the parent proxy. Results Twenty‐nine out of 31 patient/parent pairs successfully completed the Self‐PBQ. Child and parent scores demonstrated a high level of agreement with an intraclass correlation (ICC) of 0.825. In the age subgroup analysis, the ICC was 0.834 and 0.824 for the 8‐ to 9‐year‐old and 10‐ to 12‐year‐old groups, respectively. The ICC was also determined in children with type 1 VWD (ICC = 0.829) versus those with more severe bleeding disorders (ICC = 0.802). Thus, age and disease severity had no significant effect on degree of agreement. Conclusions Our study shows that agreement was maintained even in younger children aged 8–9 years and in children with varying bleeding phenotypes. This supports the administration of the modified Self‐PBQ to 8‐ to 12‐year‐old children.