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Classification of the acute emetogenicity of chemotherapy in pediatric patients: A clinical practice guideline
Author(s) -
Paw Cho Sing Edric,
Robinson Paula D.,
Flank Jacqueline,
Holdsworth Mark,
Thackray Jennifer,
Freedman Jason,
Gibson Paul,
Orsey Andrea D.,
Patel Priya,
Phillips Robert,
Portwine Carol,
Raybin Jennifer L.,
Cabral Sandra,
Sung Lillian,
Dupuis L. Lee
Publication year - 2019
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.27646
Subject(s) - medicine , guideline , antiemetic , intensive care medicine , clinical practice , pediatric oncology , chemotherapy , medline , family medicine , cancer , pathology , political science , law
This clinical practice guideline (CPG) provides clinicians with recommendations regarding chemotherapy emetogenicity classification in pediatric oncology patients. This information is critically important for the appropriate selection of antiemetic prophylaxis. Recommendations are based on a systematic review limited to pediatric patients and a framework for classification when antiemetic prophylaxis is provided. Findings of 87 publications informed the emetogenicity classification of 49 single‐agent and 13 combination‐agent regimens. Information required for the classification of many chemotherapies commonly administered to pediatric patients is lacking. In the absence of pediatric data, consultation of methodologically sound CPGs aimed at adult oncology patients may be appropriate.