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Successful treatment of a metastatic hepatocellular malignant neoplasm, not otherwise specified with chemotherapy and liver transplantation
Author(s) -
Seng Michaela S.,
Berry Bligh,
Karpelowsky Jonathan,
Thomas Gordon,
Mews Catherine,
Stormon Michael,
Shun Albert,
Cole Catherine
Publication year - 2019
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.27603
Subject(s) - hepatoblastoma , medicine , hepatocellular carcinoma , liver transplantation , chemotherapy , neoplasm , transplantation , oncology , pathology
Abstract Hepatocellular malignant neoplasm, not otherwise specified (HCN‐NOS) is a provisional entity describing a subset of rare malignant pediatric liver tumors with overlapping features of hepatoblastoma and hepatocellular carcinoma. We present a case illustration of metastatic HCN‐NOS successfully treated with a backbone of hepatoblastoma chemotherapy, pulmonary metastastectomy, and liver transplantation, along with a literature review of the clinical outcomes of HCN.