Sudden spinal hemorrhage in a pediatric case with total body irradiation‐induced cavernous hemangioma | Zendy

Mikami Takashi | Zendy; Kato Itaru | Zendy; Nozaki Fumihito | Zendy; Umeda Katsutsugu | Zendy; Kamitori Tatsuya | Zendy; Tasaka Keiji | Zendy; Ogata Hideto | Zendy; Hiramatsu Hidefumi | Zendy; Arakawa Yoshiki | Zendy; Adachi Souichi | Zendy

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Sudden spinal hemorrhage in a pediatric case with total body irradiation‐induced cavernous hemangioma

Author(s) -

Mikami Takashi,

Kato Itaru,

Nozaki Fumihito,

Umeda Katsutsugu,

Kamitori Tatsuya,

Tasaka Keiji,

Ogata Hideto,

Hiramatsu Hidefumi,

Arakawa Yoshiki,

Adachi Souichi

Publication year - 2018

Publication title -

pediatric blood and cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.116

H-Index - 105

eISSN - 1545-5017

pISSN - 1545-5009

DOI - 10.1002/pbc.27250

Subject(s) - medicine , hemangioma , magnetic resonance imaging , total body irradiation , regimen , surgery , adverse effect , radiation therapy , radiology , chemotherapy , cyclophosphamide

Compared to cerebral radiation‐induced cavernous hemangiomas (RICHs), little is known about intraspinal RICHs. A 13‐year‐old male suddenly developed symptomatic spinal hemorrhage eight years after hematopoietic stem cell transplantation using a total body irradiation (TBI) based myeloablative regimen. A solitary small hemangioma was detected on follow‐up T2 star weighted magnetic resonance imaging of the spine. His neurological symptoms gradually improved with supportive treatment and rehabilitation, although he experienced rebleeding 2 years later. Intraspinal RICH is very rare but should be recognized as a possible late adverse effect in pediatric patients who received TBI.

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