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Thyroid cancer in adolescents and young adults
Author(s) -
Massimino Maura,
Evans Douglas B.,
Podda Marta,
Spinelli Claudio,
Collini Paola,
Pizzi Natalia,
Bleyer Archie
Publication year - 2018
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.27025
Subject(s) - medicine , overdiagnosis , thyroid cancer , thyroid carcinoma , context (archaeology) , pediatrics , cancer , thyroid , medullary cavity , young adult , oncology , paleontology , biology
In adolescents and young adults, thyroid cancer accounts for 13% of all invasive neoplasms, being three times more frequent in females, but overdiagnosis and overtreatment are common. There are two therapeutic approaches, one radical and no longer preferred in all instances, and the other conservative. Permanent complications of surgery and metabolic irradiation can affect quality of life and carry an economic burden. The overall survival rate approaches 100% for patients with differentiated thyroid cancer regardless of the extent of treatment. Medullary thyroid carcinoma is a very different entity, occurring most frequently in the context of hereditary tumor susceptibility syndromes.