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Imaging and management of fetuses and neonates with alloimmune thrombocytopenia
Author(s) -
Kovanlikaya Arzu,
Tiwari Priyanka,
Bussel James B.
Publication year - 2017
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.26690
Subject(s) - medicine , neonatal alloimmune thrombocytopenia , magnetic resonance imaging , fetus , intracranial bleeding , pregnancy , radiology , computed tomography , intensive care medicine , obstetrics , pediatrics , surgery , anticoagulant , genetics , biology
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is the most common cause of severe neonatal thrombocytopenia and intracranial bleeding in term newborns. Intracranial hemorrhage (ICH) commonly results in death or severe, lasting neurologic disability. The timing of ICH is also important for management of the next affected pregnancy in cases of FNAIT. This manuscript reviews the advantages and disadvantages of the different radiologic methodologies to identify and characterize ICH. It discusses the limits of ultrasound and the advantages of magnetic resonance imaging allowing avoidance of the radiation associated with computed tomography (CT) scans.