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Refractory cytopenias secondary to copper deficiency in children receiving exclusive jejunal nutrition
Author(s) -
Jacobson Amanda E.,
Kahwash Samir B.,
Chawla Anjulika
Publication year - 2017
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.26617
Subject(s) - copper deficiency , medicine , parenteral nutrition , anemia , gastroenterology , neutropenia , enteral administration , duodenum , population , malnutrition , pediatrics , copper , chemotherapy , chemistry , environmental health , organic chemistry
Copper deficiency is a known cause of anemia and neutropenia that is easily remedied with copper supplementation. Copper is primarily absorbed in the stomach and proximal duodenum, so patients receiving enteral nutrition via methods that bypass this critical region may be at increased risk for copper deficiency. In pediatrics, postpyloric enteral feeding is increasingly utilized to overcome problems related to aspiration, severe reflux, poor gastric motility, and gastric outlet obstruction. However, little is known about the prevalence of copper deficiency in this population. We describe three pediatric patients receiving exclusive jejunal feeds who developed cytopenias secondary to copper deficiency.