Premium
Combating blood stream infections during induction chemotherapy in children with acute myeloid leukemia: Single center results in India
Author(s) -
Subburaj Divya,
Uppuluri Ramya,
Jayaraman Dhaarani,
Vellaichamyswaminathan Venkateshwaran,
Kandath Sathishkumar,
Raj Revathi
Publication year - 2017
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.26517
Subject(s) - medicine , induction chemotherapy , myeloid leukemia , sepsis , single center , chemotherapy , complication , intensive care medicine , leukemia , myeloid , immunology , oncology
Optimal management of infectious complication is the biggest challenge in children receiving chemotherapy for acute myeloid leukemia (AML). We have analyzed the data of children undergoing AML induction chemotherapy at our center from 2002 to 2016 and found that Gram‐negative infections are more predominant when compared to the published literature. There also has been a surge in multidrug‐resistant (MDR) infections over the last 4 years, which has increased the need for supportive care and escalated the cost of care. We have introduced certain novel methods to combat MDR sepsis and decrease mortality rates.