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Forced deflation pulmonary function test: a novel method to evaluate lung function in infants and young children
Author(s) -
Goyal Rakesh K.,
Ibrahimova Azada,
Escolar Maria L.,
Szabolcs Paul,
Vander Lugt Mark T.,
Windreich Randy M.,
Weiner Daniel J.
Publication year - 2017
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.26356
Subject(s) - medicine , pulmonary function testing , vital capacity , pediatrics , pulmonary compliance , lung , lung function , cardiology , diffusing capacity
We describe the safety and feasibility of a forced deflation pulmonary function test (dPFT) in infants and young children. Fifty‐two dPFT studies were performed in 26 patients (median age, 1.4 years). Forced vital capacity (FVC) and forced expiratory flow (FEF 75 ) were normal in all except one case, but respiratory system compliance (Crs) was reduced in 24% patients. There were no significant differences in pre‐blood and marrow transplantation FVC, FEF 75 , and Crs between those patients who did and those who did not have posttransplant pulmonary complications. A larger study is needed to determine the prevalence and significance of PFT abnormalities in this age group.