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A Pediatric Case of Metastatic Conventional Parosteal Osteosarcoma Treated With Multidrug Chemotherapy
Author(s) -
Nodomi Seishiro,
Umeda Katsutsugu,
Okamoto Takeshi,
Saida Satoshi,
Hiramatsu Hidefumi,
Watanabe Kenichiro,
Adachi Souichi,
Heike Toshio
Publication year - 2016
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.26052
Subject(s) - medicine , osteosarcoma , chemotherapy , sarcoma , adjuvant chemotherapy , blood cancer , radiology , surgery , cancer , pathology , breast cancer
Parosteal osteosarcoma (POS) is conventionally a low‐grade sarcoma with limited metastatic potential; however, the tumor occasionally transforms into a high‐grade dedifferentiated POS, which commonly metastasizes to distant organs. The present report describes a rare pediatric case of conventional POS with no dedifferentiated component yet had multiple pulmonary metastases at initial diagnosis. Following limb‐sparing surgery and osteosarcoma‐oriented neoadjuvant chemotherapy, the patient received total resection of pulmonary metastases. Despite no treatment for pulmonary recurrence 1 year after adjuvant chemotherapy, the patient is alive with stable disease 4 years and 6 months after the initial diagnosis.