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Brainstem‐sparing craniospinal irradiation delivered with pencil beam scanning proton therapy
Author(s) -
HillKayser Christine,
Kirk Maura
Publication year - 2015
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.25378
Subject(s) - pencil beam scanning , medicine , brainstem , proton therapy , radiation therapy , ependymoma , nuclear medicine , irradiation , radiology , physics , nuclear physics
Delivery of craniospinal irradiation (CSI) is a curative approach to recurrent ependymoma, but is associated with risks from re‐irradiation, particularly of the brainstem. Pencil beam scanning proton therapy allows delivery of CSI with sparing of normal tissues. Here, we describe a case of brainstem‐sparing CSI that resulted in excellent coverage of the craniospinal axis with minimal radiation to brainstem. This is a novel concept that compares favorably to previously described methods using x‐rays that may result in underdosing of surrounding tissues in effort to spare brainstem. Pediatr Blood Cancer 2015;62:718–720. © 2015 Wiley Periodicals, Inc.