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Successful treatment of intraocular post‐transplant lymphoproliferative disorder with intravenous rituximab
Author(s) -
Iu Lawrence P.,
Yeung Jane C.,
Loong Florence,
Chiang Alan K.
Publication year - 2015
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.25223
Subject(s) - medicine , rituximab , post transplant lymphoproliferative disorder , intraocular lymphoma , uveitis , lymphoproliferative disorders , lymphoma , dermatology , gastroenterology , surgery , ophthalmology
We reported a rare case of intraocular post‐transplant lymphoproliferative disorder (PTLD) arising in a 3‐year‐old liver transplant recipient who had a prior history of systemic PTLD. The first PTLD entered remission after treatment with intravenous rituximab and withdrawal of immunosuppressants. One year after remission, she presented with granulomatous uveitis and iris nodules in the right eye. Iris biopsy confirmed recurrence of intraocular PTLD, which resolved completely after a second course of intravenous rituximab. Pediatr Blood Cancer 2015;62:169–172. © 2014 Wiley Periodicals, Inc.