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Steroid‐induced ocular hypertensive response in children and adolescents with acute lymphoblastic leukemia and non‐hodgkin lymphoma
Author(s) -
de Queiroz Mendonca Cristiano,
de Souza Cristiano Prado,
MartinsFilho Paulo Ricardo Saquete,
Viana Simone Santana,
Leal Bruno Campelo,
Cipolotti Rosana
Publication year - 2014
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.25070
Subject(s) - medicine , lymphoblastic leukemia , lymphoblastic lymphoma , lymphoma , prospective cohort study , blindness , intraocular pressure , leukemia , pediatrics , ophthalmology , immunology , optometry , immune system , t cell
The aim of this study was to evaluate intraocular pressure (IOP) associated with use of glucocorticoids in children and adolescents treated for acute lymphoblastic leukemia and non‐Hodgkin lymphoma. We carried out a prospective descriptive study with measurement of IOP before treatment (D0), 8th (D8), 14th (D14), and 28h days (D28) of treatment. We examined 12 patients, with two cases of ocular hypertension, and it was found a statistically significant difference between the means of IOP between D0 versus D8 and D0 versus D14 ( P = 0.013). The possibility of silent ocular hypertension with irreversible blindness indicates the need of IOP verification. Pediatr Blood Cancer 2014;61:2083–2085. © 2014 Wiley Periodicals, Inc.