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Brain development, experience, and behavior
Author(s) -
Kolb Bryan,
Mychasiuk Richelle,
Gibb Robbin
Publication year - 2014
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.24908
Subject(s) - synaptogenesis , medicine , brain development , neurogenesis , neuroscience , neural development , neuroplasticity , psychological intervention , psychiatry , psychology , biochemistry , chemistry , gene
Brain development progresses through a series of stages beginning with neurogenesis and progressing to neural migration, maturation, synaptogenesis, pruning, and myelin formation. This review examines the literature on how early experiences alter brain development, including environmental events such as sensory stimuli, early stress, psychoactive drugs, parent‐child relationships, peer relationships, intestinal flora, diet, and radiation. This sensitivity of the brain to early experiences has important implications for understanding neurodevelopmental disorders as well as the effect of medical interventions in children. Pediatr Blood Cancer 2014; 61:1720–1723. © 2013 Wiley Periodicals, Inc.