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Exercise training in childhood cancer survivors with subclinical cardiomyopathy who were treated with anthracyclines
Author(s) -
Smith Webb A.,
Ness Kirsten K.,
Joshi Vijaya,
Hudson Melissa M.,
Robison Leslie L.,
Green Daniel M.
Publication year - 2014
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.24850
Subject(s) - medicine , subclinical infection , cardiomyopathy , anthracycline , physical therapy , pediatric cancer , heart failure , cancer , cardiology , breast cancer
Childhood cancer survivors (CCS) treated with anthracyclines are at risk for cardiomyopathy. This case series evaluated the response of anthracycline exposed CCS with subclinical cardiomyopathy to aerobic and strength training. Body composition, strength and cardiopulmonary fitness were evaluated before and after the 12‐week intervention. All equipment and materials were provided to five 10+ year CCS (3 males, mean age 38.0 ± 3.3 years) for a guideline‐based home exercise program. All five completed the study with no adverse events. Compliance with exercise was 86%. These results suggest that exercise training may improve exercise capacity of CCS with subclinical cardiomyopathy. Pediatr Blood Cancer 2014;61:942–945. © 2013 Wiley Periodicals, Inc.