Premium
Increased incidence of retroperitoneal teratomas and decreased incidence of sacrococcygeal teratomas in infants with Down syndrome
Author(s) -
Kobayashi Tetsuko,
Sakemi Yoshihiro,
Yamashita Hironori
Publication year - 2014
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.24693
Subject(s) - medicine , incidence (geometry) , blood cancer , teratoma , sacrococcygeal teratoma , population , pediatrics , cancer , pathology , pregnancy , fetus , genetics , biology , physics , environmental health , optics
Individuals with Down syndrome (DS) have a unique profile of neoplasms, with a higher incidence of leukemias and a lower incidence of solid tumors than seen in the general population. We recently encountered two cases of infants with DS with retroperitoneal teratoma. After reviewing the literature on teratomas in DS, we found that the incidence of retroperitoneal teratomas was higher and the incidence of sacrococcygeal teratomas was lower in infants with DS than in the general population. Pediatr Blood Cancer 2014;61:363–365. © 2013 Wiley Periodicals, Inc.