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Motor functioning during and following treatment with chemotherapy for pediatric acute lymphoblastic leukemia
Author(s) -
Green Jessica L.,
Knight Sarah J.,
McCarthy Maria,
De Luca Cinzia R.
Publication year - 2013
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.24537
Subject(s) - medicine , gross motor skill , blood cancer , lymphoblastic leukemia , pediatrics , motor skill , population , physical medicine and rehabilitation , cancer , leukemia , psychiatry , environmental health
This systematic review evaluated empirical studies examining motor skills in children during and following treatment for acute lymphoblastic leukemia. Most studies indicated that children on‐treatment display poorer gross and fine motor abilities than healthy peers, but generally have intact visual‐motor integration skills. Studies have reported gross motor difficulties in 5–54% of survivors. There is some limited evidence for long‐term fine motor deficits. The evidence for visual‐motor integration difficulties in the survivor population is less consistent. Larger studies with a longitudinal design are needed to further specify the onset and timing of motor difficulties and ascertain risk factors. Pediatr Blood Cancer 2013;60:1261–1266. © 2013 Wiley Periodicals, Inc.