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SIOP‐PODC recommendations for graduated‐intensity treatment of retinoblastoma in developing countries
Author(s) -
Chantada Guillermo,
LunaFineman Sandra,
Sitorus Rita S.,
Kruger Mariana,
Israels Trijn,
LealLeal Carlos,
Bakhshi Sameer,
Qaddoumi Ibrahim,
Abramson David H.,
Doz François
Publication year - 2013
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.24468
Subject(s) - retinoblastoma , medicine , enucleation , blood cancer , disease , developing country , pediatrics , intensive care medicine , cancer , surgery , biochemistry , economics , chemistry , gene , economic growth
Retinoblastoma remains incurable in many regions of the world. The major obstacles to cure are delayed diagnosis, poor treatment compliance, and lack of evidence‐based recommendations for clinical management. Although enucleation is curative for intraocular disease, in developing countries retinoblastoma is often diagnosed after the disease has disseminated beyond the eye. A SIOP‐PODC committee generated guidelines for the clinical management of retinoblastoma in developing countries and developed a classification system based on the resources available in those settings. Recommendations are provided for staging and treatment of unilateral and bilateral retinoblastoma and counseling of families for whom compliance is an issue. Pediatr Blood Cancer 2013; 60: 719–727. © 2013 Wiley Periodicals, Inc.