Lymphoproliferative disorder that resembles heptosplenic lymphoma during maintenance treatment for T‐cell acute lymphoblastic leukemia | Zendy

Hu YouJun | Zendy; Ahmed Tahmeena | Zendy; Zaslav AnnLeslie | Zendy; Golightly Marc | Zendy; Spitzer Silvia G. | Zendy; Raetz Elizabeth | Zendy; Chan Edward L. | Zendy

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Lymphoproliferative disorder that resembles heptosplenic lymphoma during maintenance treatment for T‐cell acute lymphoblastic leukemia

Author(s) -

Hu YouJun,

Ahmed Tahmeena,

Zaslav AnnLeslie,

Golightly Marc,

Spitzer Silvia G.,

Raetz Elizabeth,

Chan Edward L.

Publication year - 2013

Publication title -

pediatric blood and cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.116

H-Index - 105

eISSN - 1545-5017

pISSN - 1545-5009

DOI - 10.1002/pbc.24442

Subject(s) - hepatosplenomegaly , medicine , lymphoblastic lymphoma , lymphoma , blood cancer , pleural effusion , chemotherapy , lymphoblastic leukemia , leukemia , pathology , cancer , immunology , t cell , disease , immune system

A 6‐year‐old male presented with a testicular mass, hepatosplenomegaly, and a pleural effusion while undergoing maintenance chemotherapy for treatment of T‐cell acute lymphoblastic leukemia (T‐ALL). He was subsequently diagnosed with a lymphoproliferative disorder that resembled hepatosplenic lymphoma (HSL). While the extranodal presentation and the protracted yet aggressive clinical course are consistent with HSL, the findings of monosomy 8 and polymorphic cell populations are unique and have not been previously described in this type of lymphoma. Pediatr Blood Cancer 2013; 60: E10–E12. © 2013 Wiley Periodicals, Inc.

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