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SIOP PODC: Clinical guidelines for the management of children with Wilms tumour in a low income setting
Author(s) -
Israels Trijn,
Moreira Claude,
Scanlan Trish,
Molyneux Liz,
Kampondeni Sam,
Hesseling Peter,
Heij Hugo,
Borgstein Eric,
Vujanic Gordan,
PritchardJones Kathy,
Hadley Larry
Publication year - 2013
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.24321
Subject(s) - medicine , wilms tumour , malnutrition , intensive care medicine , wilms' tumor , presentation (obstetrics) , disease , chemotherapy , pediatrics , surgery
Wilms tumour is a relatively common and curable paediatric tumour. Known challenges to cure in low income countries are late presentation with advanced disease, malnutrition, failure to complete treatment and limited facilities. In this article, management recommendations are given for a low income setting where only the minimal requirements for treatment with curative intent are available (setting 1). These include general management, supportive care, social support and registration of patients. Recommendations specific for Wilms tumour care include diagnostic procedures with emphasis on the role of ultrasonography, preoperative chemotherapy with a reduced dosage for malnourished children and postoperative chemotherapy based on surgical staging. Pediatr Blood Cancer 2013; 60: 5–11. © 2012 Wiley Periodicals, Inc.