Leukapheresis in children weighing less than 20 kg | Zendy

Sauer Harald | Zendy; Roland Haase | Zendy; Ulla Lieser | Zendy; Ortrud Diwan | Zendy; Jürgen Föll | Zendy

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Leukapheresis in children weighing less than 20 kg

Author(s) -

Sauer Harald,

Roland Haase,

Ulla Lieser,

Ortrud Diwan,

Jürgen Föll

Publication year - 2012

Publication title -

pediatric blood and cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.116

H-Index - 105

eISSN - 1545-5017

pISSN - 1545-5009

DOI - 10.1002/pbc.24048

Subject(s) - medicine , leukapheresis , apheresis , blood cancer , surgery , pediatric cancer , cancer , stem cell , platelet , genetics , cd34 , biology

Augmentation of standard chemotherapy with peripheral blood stem cells (PBSC) rescue is a standard treatment strategy. However, in pediatric patients weighing less than 20 kg, the collection of PBSC presents a challenge. We report our experience with nine pediatric patients weighing between 4.33 and 19.9 kg and a total of 23 PBSC collection aphereses. None of our patients experienced any major complications. We conclude that PBSC apheresis in children is a safe method. It should be based on a standardized procedure that includes the determination of clinical and laboratory parameters and appropriate monitoring. Pediatr Blood Cancer 2012; 58: 627–629. © 2011 Wiley Periodicals, Inc.

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