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Pediatric oncology research in low income countries: Ethical concepts and challenges
Author(s) -
Denburg Avram E.,
Joffe Steven,
Gupta Sumit,
Howard Scott C.,
Ribeiro Raul C.,
Antillon Federico A.,
Vasquez Roberto,
Sung Lillian
Publication year - 2012
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.23419
Subject(s) - pediatric oncology , medicine , blood cancer , context (archaeology) , informed consent , developing country , research ethics , knowledge translation , pediatric cancer , childhood cancer , translational research , family medicine , medical education , alternative medicine , cancer , knowledge management , economic growth , pathology , paleontology , psychiatry , computer science , economics , biology
Uneven strides in research and care have led to discrepancies in childhood cancer outcomes between high and low income countries (LICs). Collaborative research may help improve outcomes in LICs by generating knowledge for local scientific communities, augmenting knowledge translation, and fostering context‐specific evaluation of treatment protocols. However, the risks of such research have received little attention. This paper investigates the relationship between pediatric oncology research in LICs and four core issues in the ethics literature: standard of care, trial benefits, ethics review, and informed consent. Our aims are to highlight the importance of this field and the need for further inquiry. Pediatr Blood Cancer 2012; 58: 492–497. © 2011 Wiley Periodicals, Inc.