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Prevention of bacterial infection in pediatric oncology: What do we know, what can we learn?
Author(s) -
Alexander Sarah,
Nieder Michael,
Zerr Danielle M.,
Fisher Brian T.,
Dvorak Christopher C.,
Sung Lillian
Publication year - 2011
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.23416
Subject(s) - medicine , blood cancer , pediatric oncology , intensive care medicine , sepsis , pediatric cancer , antimicrobial , cancer , cancer therapy , chemistry , organic chemistry
Bacterial sepsis continues to be a leading cause of morbidity and toxic death in children receiving intensive therapy for cancer. Empiric therapy for suspected infections and treatment of documented infections are well‐established standards of care. The routine use of prophylactic strategies is much less common in pediatric oncology. This paper will review the current literature on the use and risks of antimicrobial prophylaxis as well as non‐pharmacological methods for infection prevention and will address areas in need of further research. Pediatr Blood Cancer 2012; 59: 16–20. © 2011 Wiley Periodicals, Inc.