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Cardiac metastasis and hypertrophic osteoarthropathy in recurrent infantile fibrosarcoma
Author(s) -
Shah Nirali N.,
Price Mitchell R.,
Loeb David M.
Publication year - 2011
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.23321
Subject(s) - medicine , hypertrophic osteoarthropathy , metastasis , fibrosarcoma , autopsy , metastatic lesion , lung , pathology , lesion , cancer
Cardiac metastasis and hypertrophic osteoarthropathy are both quite rare. We describe a patient presenting with hypertrophic osteoarthropathy as the first symptom of recurrent infantile fibrosarcoma (IF). During surgical resection of lung metastasis, the patient suffered sudden cardiac arrest. Autopsy demonstrated a metastatic lesion in the intraventricular septum of the heart, which is previously undescribed in the literature. This case demonstrates that IF can be aggressive despite its more typical benign course. Pediatr Blood Cancer 2012; 59: 179–181. © 2011 Wiley Periodicals, Inc.